Season
- Season 1 2006-09-18
Episode
- Episode 1: Will Ferrell, Jenny McCarthy
- Episode 2: Eva Mendes, "So You Think You Can Dance", Granny Basketball
- Episode 3: Lisa Kudrow, 10 year-old Opera Singer, Adam Rodriguez
- Episode 4: Carol Burnett, Rainn Wilson, Hollerin' Championships
- Episode 5: Felicity Huffman, 'Animal Guys' Paul Hahn and David Riherd, Enrique Murciano
- Episode 6: Julia Louis-Dreyfus, Illusionist Criss Angel, Mario Lopez
- Episode 7: Debra Messing, Fashion Makeover with Lucky Magazine, Omar Epps
- Episode 8: George Lopez, Jennifer Finnigan, Vacuum Cleaning Genius, Tim Bagley At A Cher Convention
- Episode 9: Sela Ward, Chris Noth
- Episode 10: Patricia Heaton, Duane Martin, Jesse McCartney
- Episode 11: Jane Kaczmarek, Masi Oka, Champion Cloggers
- Episode 12: Tom Bergeron, Eric Stromer, Elizabeth Perkins
- Episode 13: Tim Daly, Domino Magazine
- Episode 14: Connie Britton, Michael Clark Duncan
- Episode 15: Jennifer Love Hewiitt, Jonny Lee Miller, J. Xavier
- Episode 16: Virginia Madsen, Noah Gray-Cabey, Around The Office
- Episode 17: Marcia Cross, Clinton Kelly, Isaiah Washington
- Episode 18: Molly Ringwald, OK Go
- Episode 19: Wanda Sykes, Goran Visnjic, Ruben Studdard
- Episode 20: Peter Gallagher, Nathan Burton, Tyler James Williams
- Episode 21: Bradley Whitford, Shelley Morrison, Eric Mabius, Mario Vazquez, Phil Pfister
- Episode 22: Cheyenne Kimball, Laura Linney, Ricardo Antonio Chavira
- Episode 23: Merv Griffin, Kim Raver, Author Jennifer Egan
- Episode 24: Rob Morrow, Rebecca Cole, Anne Heche, Joshua Bell
- Episode 25: Josh Duhamel, Alison Lohman, Authors Mark Leyner and Billy Goldberg, Aly & AJ Michalka
- Episode 26: Kristin Chenoweth, Jill Conner Browne, Nick & Aaron Carter, the Sweet Potato Queens
- Episode 27: Jamie Lee Curtis, The Mystic Pixies, Amy Smart, Taylor Swift
- Episode 28: Lauren Holly, Ruben Studdard, Daniel Dae Kim
- Episode 29: Cloris Leachman, Jensen Ackles, Dog Halloween Costumes with Teri Austin, ecostylist Danny Seo
- Episode 30: James Denton, Yahoo 9's Maria Sansone, Angela Kinsey, JoJo
- Episode 31: Steven Weber, Audra McDonald
- Episode 32: Neil Patrick Harris, Kevin Federline
- Episode 33: Jamie Kennedy, Jeffrey Sebelia, Meat Loaf, Card Thrower Rick Smith
- Episode 34: Clay Aiken, Tysonia Tschinga "Real Life" Dancing with the Stars
- Episode 35: Sean Hayes, Eddie Cibrian, Dog Whisperer Cesar Millan, Author Mitch Albom
- Episode 36: Barry Manilow, Parminder Nagra, Tim Bagley visits "America's Got Talent", Kid's Ballroom Dancing
- Episode 37: Mark Harmon, Hip Hop Champions, Constance Zimmer, Melora Hardin
- Episode 38: Kevin Nealon, Antonio Sabato Jr.
- Episode 39: Bob Saget, sex educator Sue Johanson
- Episode 40: Molly Sims, Andrea Bowen, The Ten Tenors, Celebrity trainer Michael Carson
- Episode 41: Cheryl Hines, Tim Gunn, Thanksgiving Dog Adoption Fashion Show
- Episode 42: David Hyde Pierce, Linda Cardellini, Taylor Ware
- Episode 43: Patricia Arquette, Champion Pirouette Dancer, Daily Candy Trends
- Episode 44: Dax Shepard, Tom Arnold, Kimberley Locke
- Episode 45: Reba McEntire, Patrick Wilson, RBD
- Episode 46: Tom Bergeron, Trista and Ryan, Benji Schwimmer, Rupert Boneham
- Episode 47: Sharon Stone, Scott Foley, Rusty Schwimmer, Paz Vega, Danny Seo
- Episode 48: Wayne Brady, Penguins Pete and Penny, Nestle Toll House Bake Sale Finalist
- Episode 49: Camryn Manheim, Phil Pfister, James Lesure, Author Karen Rizzo
- Episode 50: Neil Patrick Harris, Josh Radnor, Alyson Hannigan, Jason Segel and Cobie Smulders
- Episode 51: David Boreanaz, Julianne Nicholson, Bianca Ryan
- Episode 52: Matthew Broderick, Donald Faison, Brian Baumgartner, the Bucket Boys, Catherine Lloyd Burns
- Episode 53: Tracy Morgan, Melissa Peterman, Jarod Miller, Eric Stromer
- Episode 54: Carrie Fisher, Paul Rodriguez, Nadine Velazquez
- Episode 55: Rosanna Arquette, Tom Green, Adrian Pasdar
- Episode 56: Marla Sokoloff, Taylor Hicks, "Campus Ladies"
- Episode 57: Phyllis Diller
- Episode 58: Carson Kressley, Beau Bridges, Amy Sedaris
- Episode 59: Wendie Malick, Janice Dickinson
- Episode 60: John Stamos, Brenda Strong, Cris Judd, Tyrese
- Episode 61: David James Elliott, Michael Ealy, Lisa Edelstein, magician Nathan Burton
- Episode 62: Jeffrey Tambor, Tisha Campbell, designer Mark Montano, Hall & Oates
- Episode 63: Shawn and Marlon Wayans, Taylor Hicks
- Episode 64: Oded Fehr, Rob Morrow, Rhea Perlman, Sarah Rush
- Episode 65: Howie Mandel, Jennie Garth, Ahmet Zappa, psychic medium Lisa Williams
- Episode 66: Jane Seymour, David Conrad, Ken Davitian, Joshua Radin
- Episode 67: Alfre Woodard, Milo Ventimiglia, Fantasia Barrino
- Episode 68: Billy Ray Cyrus, Richard Simmons, authors of "Party Confidential"
- Episode 69: Hall & Oates, Brian McKnight, Clay Aiken, José Feliciano, Kimberley Locke, Celtic Woman
- Episode 70: Emily Procter, Tichina Arnold, Goo Goo Dolls
- Episode 71: Natalie Cole, Craig Bierko, Dave Annable, Blaine Zuckerman
- Episode 72: Tom Bergeron, Tim Daly, Will Ferrell, Allison Janney, Davy Jones, Chris Noth, Jerry Springer
- Episode 73: Patricia Heaton, Cheryl Hines, Debra Messing, Christine Taylor
- Episode 74: Josh Duhamel, Jamie Kennedy, George Lopez, Mario Lopez
- Episode 75: Selma Blair, Kristin Chenoweth, Lisa Kudrow, Laura Linney, Julia Louis-Dreyfus
- Episode 76: Chandra Wilson, Jesse Bradford, Clay Aiken
The Megan Mullally Show Season 1 Sela Ward, Chris Noth
Two-time Emmy Award-winner Megan Mullally, coming off eight seasons as wisecracking socialite Karen Walker on NBC's "Will & Grace," moves into the driver's seat as host for this daytime talk show. Each episode is an entertaining hour featuring a mix of celebrities, real people, music, and comedy. Megan will interview top celebrities and also introduce the world to guests of all kinds — from quirky characters to funny kids to offbeat experts.
